![]() ![]() “The fun thing has been to create something new and to create something that will have meaning for them. “If you present the audience with a story in a language they understand and with a story that means something to them, they come and they consume the entertainment and enjoy it,” Radford said. Lucinda learns that it doesn’t matter what you give at Christmas, as long as you give from the heart. ![]() When she offers the gift at the altar, the weeds bloom into beautiful poinsettias. On her way to church she picks a few weeds from the side of the road as a gift and worries this might not be good enough for the nativity scene. Lucinda leaves to celebrate Christmas Eve without her mother and without a gift. Lucinda’s mother is too sick to help Lucinda finish the blanket. In this story, Lucinda and her ailing mother are making a blanket as a gift for the nativity scene at the Christmas Eve service. It’s presented mostly in English with music inspired by mariachi songs in Spanish. Mack and McGuire chose to break ground with a Mexican folk tale about poinsettias at Christmastime and the true meaning of giving. Radford said folk tales are a common operatic theme and are often based on European stories performed in foreign languages. In 2015 he commissioned composer Mack and McGuire to write an original opera for Fresno State so the opera students could perform for the children of the Central Valley. Anthony Radford, associate professor of voice and opera in Fresno State’s Music Department where he is artistic director of Fresno State Opera Theatre and the Fresno State’s Children’s Opera. ![]() Fourteen performances are scheduled this fall.ĭr. #LUCINDA KERSCHENSTEINER ADOBE DRIVE FREE#The production and the free performances are the result of a $10,000 grant awarded to the Fresno State Opera Theatre by the Central Valley Community Foundation to commission and produce the new children’s opera with part of the goal to reach communities that would benefit from seeing original live opera theatre. And two special-event performances on campus are set for this fall also. The production will also travel to various Fresno County schools during the Christmas season, beginning with a performance for school children Nov. ![]() Several free public performances are set beginning with the world premiere in Fresno on Nov. The 45-minute production, “Lucinda y las Flores de la Nochebuena” by composer Evan Mack and librettist Joshua McGuire, is based on a Mexican folktale about poinsettias at Christmas time. The T cells are further labelled with fluorescent proteins by retroviral gene transfer to perform intravital imaging by two-photon microscopy.Fresno State Opera Theatre cast members are rehearsing for an originally composed children’s opera featuring Mexican folk melodies with traditional Christmas carols that will be performed this fall for the first time. The project focuses on establishing mouse primary encephalitogenic T cells, which induce disease after adoptive transfer. To study pathological mechanisms of multiple sclerosis, we use experimental autoimmune encephalomyelitis as an animal model. Naoto Kawakami, Institut für Klinische Neuroimmunologie In this student project we want to set up a cell culture model that allows us to study the induction (and ultimately the therapeutic prevention) of such membrane changes in a simplified model. We have previously discovered that inflammation-induced changes in the neuronal membrane play a key role in the induction of axon degeneration. This is an important question as the extent of neuronal damage ultimately determines the persistent neurological deficits in MS patients. Projekt: In our laboratory we are studying how neurons are damaged in the common neuroinflammatory disease multiple sclerosis. Martin Kerschensteiner, Institut für Klinische Neuroimmunologie In this student project we want to immunhistochemical techniques to characterize the effect of semaphorin7A deficiency on the neuronal and immune response to spinal cord injury. In particular we are currently trying to understand the role of synaptogenic molecules in helping axons remodel following injury. Projekt: In our laboratory we are interested in studying the anatomical, functional and molecular mechanisms underlying the recovery process following spinal cord injury in an attempt to develop new therapeutic strategies that can support axonal and functional repair. Florence Bareyre, Institut für Klinische Neuroimmunologie ![]()
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